Aerospace and Mechanical Engineering
University of Southern California
Ciliated tissue creates microfluidic habitats with distinct filtering and mixing properties
The ability to manipulate and organize the motion of micron-scale particles is relevant to numerous biological and bioindustrial applications. Examples include the transport and sorting of cells and the self-assembly of colloids in microfluidic channels. In this talk, I will present two distinct problems that examine (1) the fluid mechanics of active ciliated surfaces with emphasis on their role in mixing, transport and filtering of passive particles, and (2) the effect of geometric confinement on the collective behavior of passive and active particles. I will show new phenomena in both systems, including cilia-driven mechanisms for selective particle capture and the development of phonons and density shock waves in microfluidic channels. I will conclude by commenting on how these models can be used to assess the fitness of ciliated surfaces and to guide the design of novel mechanisms for controlling particle transport in microchannels.