Latino Studies at New York University

Calvin Zhang

Courant Institute of Mathematical Sciences
New York University

October 20, 2015

A benefit of randomness in synaptic vesicle release

This is joint work done in collaboration with Charles S. Peskin

Noise is not only a source of disturbance, but it also can be beneficial for neuronal information processing. The release of neurotransmitter vesicles in synapses is an unreliable process, especially in the central nervous system. Here we show that the probabilistic nature of neurotransmitter release directly influences the functional role of a synapse, and that a small probability of release per docked vesicle helps reduce the error in the reconstruction of desired signals from the time series of vesicle release events.